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Simultaneous determination of nine tyrosine kinase inhibitors by 96-well solid-phase extraction and ultra performance LC/MS-MS

✍ Scribed by Stéphane Bouchet; Emmanuelle Chauzit; Dominique Ducint; Nadège Castaing; Mireille Canal-Raffin; Nicholas Moore; Karine Titier; Mathieu Molimard

Book ID
116349078
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
599 KB
Volume
412
Category
Article
ISSN
0009-8981

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## Abstract This paper describes a method for determining 11 pharmaceuticals in various water sources by SPE followed by LC‐(ESI) MS. SPE was carried out with Oasis^TM^ HLB and the recoveries were 33–67% for 250 and 100 mL sewage water, 55–77% for 500 mL river water and 72–98% for 1 L tap water, wi