Simultaneous determination of mixtures of organic acids or bases based on the differences in the titration spectra

✍ Scribed by Zhongliang Zhu; Tonghua Li; Peisheng Cong; Zifeng Deng

• Publisher: Elsevier Science
• Year: 1999
• Tongue: English
• Weight: 104 KB
• Volume: 45
• Category: Article
• ISSN: 0169-7439
• DOI: 10.1016/s0169-7439(98)00103-8

✦ Synopsis

Based on the differences in titration spectra, mixtures of organic acids with similar p K were determined simultaneously. a Principal component regression calibration was used for the evaluation of titration spectra. The effects of differences in p K a and sampling interval of pH on accuracy were studied in detail. Combining precipitation and the acid-base reaction of organic acid, precipitation-acid-base titrimetry is proposed. The mixture of acids with almost the same p K can be detera mined simultaneously and accurately only if their p K values are different. Synthetic mixtures of isomer of chlorobenzoic sp acid and homologue of phenol were determined simultaneously and acceptable results were obtained.