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Simultaneous determination of lercanidipine, benazepril and benazeprilat in plasma by LC–MS/MS and its application to a toxicokinetics study

✍ Scribed by Keguang Chen; Jing Zhang; Sha Liu; Dujuan Zhang; Yanni Teng; Chunmin Wei; Benjie Wang; Xiaoyan Liu; Guiyan Yuan; Rui Zhang; Wenjing Zhao; Ruichen Guo

Book ID
116620766
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
830 KB
Volume
899
Category
Article
ISSN
1873-376X

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Simultaneous determination of atorvastat
Simultaneous determination of atorvastatin, amlodipine, ramipril and benazepril in human plasma by LC-MS/MS and its application to a human pharmacokinetic study
✍ Nageswara Rao Pilli; Jaswanth Kumar Inamadugu; Ramesh Mullangi; Vijaya Kumari Ka 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 943 KB

## Abstract A rapid, simple, sensitive and specific LC‐MS/MS method has been developed and validated for the simultaneous estimation of atorvastatin (ATO), amlodipine (AML), ramipril (RAM) and benazepril (BEN) using nevirapine as an internal standard (IS). The API‐4000 LC‐MS/MS was operated under t