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Simultaneous determination of difloxacin and its primary metabolite sarafloxacin in rabbit plasma

✍ Scribed by M. A. Garcia; C. Solans; J. J. Aramayona; S. Rueda; M. A. Bregante

Book ID
105593631
Publisher
Springer
Year
2000
Tongue
English
Weight
364 KB
Volume
51
Category
Article
ISSN
0009-5893

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Simultaneous determination of enrofloxacin and its primary metabolite, ciprofloxacin, in plasma by HPLC with fluorescence detection
✍ M. A. Garcia; C. Solans; J. J. Aramayona; S. Rueda; M. A. Bregante; A. de Jong πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 50 KB πŸ‘ 2 views

A simple and sensitive HPLC method has been developed for the simultaneous determination of enrofloxacin (ENR) and ciprofloxacin (CIP) in plasma. Plasma sample preparation was carried out by adding phosphate buffer (pH 7.4, 0.1 M), followed by extraction with trichloromethane. ENR, CIP and the inter