Simultaneous determination of cystathionine, total homocysteine, and methionine in dried blood spots by liquid chromatography/tandem mass spectrometry and its utility for the management of patients with homocystinuria
✍ Scribed by Bártl, Josef; Chrastina, Petr; Krijt, Jakub; Hodík, Jakub; Pešková, Karolína; Kožich, Viktor
- Book ID
- 125860041
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 889 KB
- Volume
- 437
- Category
- Article
- ISSN
- 0009-8981
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The anticancer drug etoposide is associated with leukemias with MLL gene translocations and other translocations as a treatment complication. The genotype of cytochrome P450 3A4 (CYP3A4), which converts etoposide to its catechol metabolite, influences the risk. In order to perform pharmacokinetic st
## Abstract Gemcitabine, 2′,2′‐difluoro‐2′‐deoxycytidine (dFdC) is a pyrimidine antimetabolite employed against several human malignancies. It undergoes intracellular activation to the pharmacologically active triphosphate form (dFdCTP) and metabolic inactivation to the metabolite 2′,2′‐difluorodeo
## Abstract A LC‐MS/MS method was developed and validated for the determination of cyclosporine A (CsA) and its three phase 1 metabolites AM1, AM9, and AM4N in whole blood and lymphocytes isolated on the Histopaque gradient. 200 μL of whole blood was precipitated with 10 mol/L zinc sulfate in aceto