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Simultaneous determination of bendamustine and its active metabolite, gamma-hydroxy-bendamustine in human plasma and urine using HPLC-fluorescence detector: Application to a pharmacokinetic study in Chinese cancer patients

✍ Scribed by Xie, Feifan; Cheng, Zeneng; Cheng, Hang; Yu, Peng

Book ID
122167439
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
451 KB
Volume
960
Category
Article
ISSN
1873-376X

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## Abstract A rapid, sensitive, and simple ultra‐performance liquid chromatography–tandem mass spectrometry (UPLC/MS/MS) method for the determination of udenafil and its active metabolite, DA‐8164, in human plasma and urine using sildenafil as an internal standard (IS) was developed and validated.