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Simultaneous Determination and Pharmacokinetic Study of Metformin and Rosiglitazone in Human Plasma by HPLC-ESI-MS

✍ Scribed by Chen, L.; Zhou, Z.; Shen, M.; Ma, A.

Book ID
111680925
Publisher
Preston Publications
Year
2011
Tongue
English
Weight
482 KB
Volume
49
Category
Article
ISSN
0021-9665

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## Abstract A new method for the determination of anti‐diabetic drugs metformin and rosiglitazone based on the use of capillary electrophoresis with electrospray mass spectrometry was developed. The proposed method allowed their separation within 11 min by using 50 mM formic acid at +20 kV. Positiv