We have developed a sensitive automated fluorometric method based upon the manual procedure of Denckla and Dewey [(1967) J. Lab. Clin. Med. 69, 160-1691 for determining both free and total tryptophan in plasma. Free tryptophan is measured in a series of increasingly diluted aliquots of a sample of p
Simultaneous automated determination of free and total sulfisoxazole and sulfamethoxazole in plasma and urine
β Scribed by Robert E. Weinfeld; Teh Lo Lee
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 689 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0022-3549
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## Abstract A capillary electrophoretic method for the simultaneous determination of sulfamethoxazole and trimethoprim in plasma was developed. Sulfamethoxazole and trimethoprim extracted from human plasma with ethyl acetate were analyzed at 20 kV and 25Β°C using 15 mm phosphate buffer (pH 6.2) as t
Sensitive and specific methods for the simultaneous determination of gemfibrozil (Lopid@), a lipid-lowering agent, and its metabolites in plasma and urine are described. The methods are based on a fully automated high performance liquid chromatographic (HPLC) system with fluorescence detection. Urin