A sensitive and specific high-performance liquid chromatographic method with electrochemical detection was developed for the simultaneous determination of naltrexone and its major metabolite, 6-beta-naltrexol, in human plasma. After alkalinizing 2 ml plasma samples with pH 9 sodium carbonate buffer,
✦ LIBER ✦
Simultaneous analysis of naltrexone and its major metabolite, 6-β-naltrexol, in human plasma using liquid chromatography–tandem mass spectrometry: Application to a parent-metabolite kinetic model in humans
✍ Scribed by Hwi-yeol Yun; Seong-chul Bang; Ki-cheol Lee; In-hwan Baek; Seo-pan Lee; Wonku Kang; Kwang-il Kwon
- Book ID
- 116902071
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 575 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0039-9140
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Determination of naltrexone and its majo
✍
Anna F. Davidson; Thomas A. Emm; Henry J. Pieniaszek Jr.
📂
Article
📅
1996
🏛
Elsevier Science
🌐
English
⚖ 509 KB
Simultaneous determination of prochlorpe
✍
Masaki Tashiro; Takafumi Naito; Yoshiyuki Kagawa; Junichi Kawakami
📂
Article
📅
2011
🏛
John Wiley and Sons
🌐
English
⚖ 419 KB
Simultaneous determination of apatinib a
✍
Juefang Ding; Xiaoyan Chen; Xiaojian Dai; Dafang Zhong
📂
Article
📅
2012
🏛
Elsevier Science
🌐
English
⚖ 754 KB
Simultaneous determination of apatinib a
✍
Juefang Ding; Xiaoyan Chen; Xiaojian Dai; Dafang Zhong
📂
Article
📅
2012
🏛
Elsevier Science
🌐
English
⚖ 754 KB
Apatinib, also known as YN968D1, is a novel antiangiogenic agent that selectively inhibits vascular endothelial growth factor receptor-2. Currently, apatinib is undergoing phase II/III clinical trials in China for the treatment of solid tumors. Apatinib is extensively metabolized in humans, and its
Simultaneous determination of azelastine
✍
Wuyi Zha; Linyee Shum
📂
Article
📅
2012
🏛
Elsevier Science
🌐
English
⚖ 404 KB
Simultaneous Determination of Chloroquin
✍
Tang, Caiming; Sojinu, O. Samuel
📂
Article
📅
2012
🏛
Taylor and Francis Group
🌐
English
⚖ 416 KB