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Simulations of Protein Aggregation

✍ Scribed by Shea, Joan-Emma

Book ID
122285109
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
31 KB
Volume
104
Category
Article
ISSN
0006-3495

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## Abstract Computer simulation offers unique possibilities for investigating molecular‐level phenomena difficult to probe experimentally. Drawing from a wealth of studies concerning protein folding, computational studies of protein aggregation are emerging. These studies have been successful in ca

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We review recent scattering experiments on the reversible and irreversible aggregation and gelation of globular proteins. Globular proteins are compact with a well-defined structure in the native state, but are not perfect spheres and the details of the interaction between proteins may be intricate