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Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae

✍ Scribed by Alvarez-Vasquez, Fernando; Sims, Kellie J.; Cowart, L. Ashley; Okamoto, Yasuo; Voit, Eberhard O.; Hannun, Yusuf A.


Book ID
109893754
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
575 KB
Volume
433
Category
Article
ISSN
0028-0836

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A kinetic model of overflow metabolism in Saccharomyces cerevisiae was used for simulation of aero- bic fed-batch cultivations. An inhibitory effect of ethanol on the maximum respiration of the yeast was observed in the experiments and included in the model. The model predicts respiration, biomass,