Simplified method for determining radiochemical purity of99mTc-TRODAT-1
✍ Scribed by Z. P. Chen; S. P. Wang; J. Tang; X. M. Li; C. Y. Liu; X. J. Xu; G. X. Cao
- Book ID
- 106440481
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 145 KB
- Volume
- 277
- Category
- Article
- ISSN
- 1588-2780
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## Abstract Direct preparation of the novel dopamine transporter imaging agent [^99m^Tc]TRODAT‐1 results in uncertainty concerning the labelling efficiency. Without purification of the tracer, the statistically inefficient labelling yield becomes apparent in an inadequate radiochemical purity. The
Simple and rapid chromatographic systems were used to test the radiochemical purity of eleven 99mTc-diagnostic agents. Those systems were selected which gave no oxidation or other by-products. The tests were done with equipment normally available in Nuclear Medical Departments.