Simple synthesis of 2-aminoethylphosphonic acid and related compounds
✍ Scribed by Jósef Barycki; Przemysław Mastalerz; Mirosław Soroka
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- French
- Weight
- 193 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0040-4039
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## Abstract The usefulness of hexa‐2,5‐diyn‐1‐ol as an intermediate in the synthesis of arachidonic acid, poly‐yn alcohols and docosa‐4,7,10,13,16,19‐hexaynoic acid is demonstrated. Difficulties in the partial reduction of the latter product to the corresponding all cis‐hexaenoic acid are described
Epiceanothic acid (1) is a naturally occurring, but very rare pentacyclic triterpene with a unique pentacyclic triterpene (PT) structure. An efficient synthesis of 1 starting from betulin (3) has been accomplished in 12-steps with a total yield of 10% in our study. Compound 1 and selected synthetic