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Simple Protocol for the Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones Using SnCl 2 · 2H 2 O–LiCl as an Inexpensive Catalyst System

✍ Scribed by Shailaja, M.; Manjula, A.; Rao, B. Vittal; Parvathi, Neelakantan


Book ID
120268949
Publisher
Taylor and Francis Group
Year
2004
Tongue
English
Weight
132 KB
Volume
34
Category
Article
ISSN
0039-7911

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✍ Shujang Tu; Fang Fang; Chunbao Miao; Hong Jiang; Youjian Feng; Daqing Shi; Xiang 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 93 KB

A simple effective synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives, using boric acid as catalyst, from aromatic aldehydes, 1,3-dicarbonyl compounds and urea in glacial acetic acid is described. Compared with the classical Biginelli reaction conditions, this new method has the advantage of ex