One-pot synthesis of 3,4-dihydropyrimidi
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Shujang Tu; Fang Fang; Chunbao Miao; Hong Jiang; Youjian Feng; Daqing Shi; Xiang
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Article
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2003
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Elsevier Science
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French
⚖ 93 KB
A simple effective synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives, using boric acid as catalyst, from aromatic aldehydes, 1,3-dicarbonyl compounds and urea in glacial acetic acid is described. Compared with the classical Biginelli reaction conditions, this new method has the advantage of ex