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Simple method for the synthesis of thiopyran derivatives

✍ Scribed by K. Kh. Tokmurzin; Zh. B. Dandybaev; Zh. E. Kozhabekov; Sh. A. Amirkhanov; S. Zhumagaliev

Book ID
112355193
Publisher
Springer US
Year
1984
Tongue
English
Weight
46 KB
Volume
20
Category
Article
ISSN
0009-3122

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A new synthetic route has been devised for the preparation of 2'-O-alkyl guanosine derivatives. Utilizing a strategy of minimal protection, the alkylation was performed on partly protected guanosine using an alkyl halide and a sterically hindered strong organic base.