Simple direct injection high-performance liquid chromatographic method to determine quinidine in plasma
β Scribed by Jiu Li Huang; Denis J. Morgan
- Publisher
- Elsevier Science
- Year
- 1993
- Weight
- 329 KB
- Volume
- 620
- Category
- Article
- ISSN
- 0378-4347
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π SIMILAR VOLUMES
A liquid chromatographic method for determination of theophylline by direct injection of untreated plasma samples is described. Theophylline is detected without interference from related compounds such as paraxanthine. A precolumn venting technique is used which considerably increases column life.
An HPLC method has been developed for the determination of pseudoephedrine in plasma using column switching. Preparation of the sample was simple in that only 1000 mL of water was added to 200 mL of plasma before injection. A 900 mL aliquot was injected onto the precolumn. Double distilled water was