✦ LIBER ✦

Simple and versatile synthesis of 1-pyrroline derivatives through thermal rearrangement of N-cyclopropylimines

✍ Scribed by Pedro J. Campos; Alberto Soldevilla; Diego Sampedro; Miguel A. Rodrı́guez

Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 121 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)02238-4

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✦ Synopsis

N-Cyclopropylimines rearrange under thermal conditions to give 1-pyrrolines. The effect of imine and cyclopropane substitution is explored. This methodology allows the presence of different substituents (alkyl, alkenyl, aryl) and the reaction proceeds regiospecifically.

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