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Simple and Versatile Synthesis of Optically Active 1,2-Amino Alcohols by Grignard Addition to N,O-Dibenzylglyceraldimine and -lactaldimine

✍ Scribed by Dr. Thomas Franz; Dipl.-Chem. Matthias Hein; Dipl.-Chem. Ulrich Veith; Prof. Dr. Volker Jäger; Eva-Maria Peters; Dr. Karl Peters; Prof. Dr. Hans Georg von Schnering


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
446 KB
Volume
33
Category
Article
ISSN
0044-8249

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Diastereoselective 1,2-Addition of Organ
✍ Shin-ichi Fukuzawa; Daisuke Tsuchiya; Kae Sasamoto; Kohki Hirano; Makoto Ohtaguc 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 341 KB 👁 2 views

The chiral formylferrocenes 2-5 have been readily prepared in good yields by ortho-lithiation of the TMS-blocked orunblocked aminoferrocenes and subsequent reaction with DMF. The stereochemistry of the reaction of 2 with organometallic reagents has been examined. Reactions of 2 with Grignard and org