Simple and Efficient Synthesis of (+)-Methyl 7-Benzoylpederate, a Key Intermediate toward the Mycalamides
β Scribed by Trotter, Nicholas S.; Takahashi, Shunya; Nakata, Tadashi
- Book ID
- 126924481
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 42 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1523-7060
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The Ziegler intermediate 2, previously used in three total syntheses of forskolin (1) has been synthesized efficiently from enone 3. The key transformation of this sequence is the early and stereoselective introduction of the C-6, C-7 oxygen functional groups present in the natural product. The hig