Simple and Convenient Synthesis of 3,5-Bis-(trifluoromethyl)benzylamine via Biomimetic 1,3-Proton Shift Reaction.
โ Scribed by Vadim A. Soloshonok; Manabu Yasumoto
- Book ID
- 101997515
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 14 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
AlkhPCt: [lJ]-Pmtan shii reaction of N-be4uylcnamincs la-e. derived fmm &polyfkmmalkyl-&Wxylic esters sndpenzylsmiac. was c@yzed by (-)-Wchonidlne (5-13 mol 9b) to give good yields (6749%) of any enriched (up to 36% ce) ~~y~~ d&s&es 303. The mlting pmduetp 3p-e wem readily hydrolyze4 into the mng qt
Biomimetic Reductive Amination of Fluoro Aldehydes and Ketones via (1, 3)-Proton Shift Reaction. Scope and Limitations. -Azomethine-azomethine isomerization of the fluorinated Schiff's bases ( III) and (IX) (14 examples) affords the corresponding N-benzylidene derivatives in good yields, which can