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Similarity of Force-Induced Unfolding of Apomyoglobin to Its Chemical-Induced Unfolding: An Atomistic Molecular Dynamics Simulation Approach

✍ Scribed by Choi, Ho Sup; Huh, June; Jo, Won Ho


Book ID
118515333
Publisher
Biophysical Society
Year
2003
Tongue
English
Weight
405 KB
Volume
85
Category
Article
ISSN
0006-3495

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Steered molecular dynamics (SMD), a computer simulation method for studying force-induced reactions in biopolymers, has been applied to investigate the response of protein domains to stretching apart of their terminal ends. The simulations mimic atomic force microscopy and optical tweezer experiment