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Force-induced unfolding of human telomeric G-quadruplex: A steered molecular dynamics simulation study

โœ Scribed by Hui Li; En-hua Cao; Thomas Gisler


Book ID
116297871
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
582 KB
Volume
379
Category
Article
ISSN
0006-291X

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Steered molecular dynamics simulations o
โœ Hui Lu; Klaus Schulten ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 322 KB ๐Ÿ‘ 3 views

Steered molecular dynamics (SMD), a computer simulation method for studying force-induced reactions in biopolymers, has been applied to investigate the response of protein domains to stretching apart of their terminal ends. The simulations mimic atomic force microscopy and optical tweezer experiment