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Similar Regions of Instability in Tropomyosin and Myosin Coiled Coils

โœ Scribed by Root, Douglas D.; Hall, Nakiuda; Chen, Lee; Qian, Yuxiao; Taei, Nasrin

Book ID
122177334
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
38 KB
Volume
100
Category
Article
ISSN
0006-3495

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## Synopsis CD experiments are reported for several coiled-coil species in the tyrosine/disulfide (-250-350-nm) region. Intact noncross-linked tropomyosin ( -3ยฐC) shows a negative nonsymmetric band maximal at 280 nm. This spectrum is the sum over six tyrosines/chain, and has conformational signifi

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## SYNOPSIS Measurements are presented on the time course of chain exchange among two-chain ahelical coiled coils of rabbit tropomyosin. All experiments are in a regime (temperature, protein concentration) in which coiled-coil dimers are the predominant species. Self-exchange in rue-tropomyosin wa