Similar polypeptide composition of fast-transported proteins in rat motor and sensory axons
β Scribed by Bisby, M. A.
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 721 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0022-3034
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A previous study revealed a characteristic alteration in the ratio of labeling of two fast axonally transported polypeptides identified as S1 (22,000 daltons) and S: ! (18,000 daltons) and their ratio (Sz/S1) in rat motoneuron axons following axonal injury and subsequent regeneration. In this study
Post-Golgi trafficking of the major fast axonally transported (FT) proteins was investigated in the rat optic pathway. Following intra-ocular injection of 35 Smethionine, radiolabeled FT proteins in the optic tract (OT) and superior colliculus (SC) were analyzed by twodimensional polyacrylamide gel
## Abstract Previously, we identified calcium/calmodulinβdependent protein kinase IIΞ² (CaMKIIΞ²) mRNA in spinal motor neurons with 372 bp inserted in what corresponds to the βassociationβ domain of the protein. This was interesting because known additions and deletions to CaMKIIΞ² mRNA are usually le