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Similar polypeptide composition of fast-transported proteins in rat motor and sensory axons

✍ Scribed by Bisby, M. A.


Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
721 KB
Volume
8
Category
Article
ISSN
0022-3034

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Prolonged alteration in composition of f
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A previous study revealed a characteristic alteration in the ratio of labeling of two fast axonally transported polypeptides identified as S1 (22,000 daltons) and S: ! (18,000 daltons) and their ratio (Sz/S1) in rat motoneuron axons following axonal injury and subsequent regeneration. In this study

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Post-Golgi trafficking of the major fast axonally transported (FT) proteins was investigated in the rat optic pathway. Following intra-ocular injection of 35 Smethionine, radiolabeled FT proteins in the optic tract (OT) and superior colliculus (SC) were analyzed by twodimensional polyacrylamide gel

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## Abstract Previously, we identified calcium/calmodulin‐dependent protein kinase IIΞ² (CaMKIIΞ²) mRNA in spinal motor neurons with 372 bp inserted in what corresponds to the β€œassociation” domain of the protein. This was interesting because known additions and deletions to CaMKIIΞ² mRNA are usually le