Silver triflate-promoted coupling reactions of benzylic and allylic sulfides with O-silylated enolates of ketones and esters, a synthesis of (±)-ar-turmerone

α-Alkylation of ketones, esters, and lac

α-Alkylation of ketones, esters, and lactones: zinc bromide-catalysed alkylation of o-silylated enolates, a synthesis of (±)-ar-turmerone

✍ Ian Paterson 📂 Article 📅 1979 🏛 Elsevier Science 🌐 French ⚖ 125 KB

O-Silylated ketone enolates can be alkylated regiospecifically with t-alkyl halides in the presence of an equivalent of titanium tetrachloride; 2 for the alkylation of lithium enolates, in general, dialkylation,3 loss of regiospecificity,3 and self-condensation4 are common problems. Alternative me