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Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells

✍ Scribed by Agarwal, Chapla; Singh, Rana P; Dhanalakshmi, Sivanandhan; Tyagi, Anil K; Tecklenburg, Marianne; Sclafani, Robert A; Agarwal, Rajesh


Book ID
110068239
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
332 KB
Volume
22
Category
Article
ISSN
0950-9232

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Expression of protein kinase C Ξ²1 confer
✍ Patrizia Cesaro; Elisabetta Raiteri; Marina DΓ©moz; Roberta Castino; Francesco M. πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 173 KB

The expression of different protein kinase C (PKC) isoenzymes has been shown to vary with proliferation rates, differentiation or apoptosis in normal colon crypts. In addition, the activity of some PKC isoenzymes appears to be reduced in colorectal cancer. The aim of the present work was to determin