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Sildenafil (Viagra) ameliorates clinical symptoms and neuropathology in a mouse model of multiple sclerosis

✍ Scribed by Paula Pifarre; Judith Prado; María Antonia Baltrons; Merce Giralt; Pere Gabarro; Douglas L. Feinstein; Juan Hidalgo; Agustina Garcia


Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
848 KB
Volume
121
Category
Article
ISSN
0001-6322

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## Abstract We tested cortical motor evoked potentials (cMEPs) as a quantitative marker for in vivo monitoring of corticospinal tract damage in a murine multiple sclerosis model (experimental autoimmune encephalomyelitis, EAE). The cMEPs, previously standardized in naive C57BL/6 developing and adul