Significantly shorter telomeres in T-cells of patients with ZAP-70+/CD38+ chronic lymphocytic leukaemia
✍ Scribed by Alexander Röth; Dirk De Beer; Holger Nückel; Ludger Sellmann; Ulrich Dührsen; Jan Dürig; Gabriela M. Baerlocher
- Book ID
- 108675975
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 217 KB
- Volume
- 143
- Category
- Article
- ISSN
- 0007-1048
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## Abstract ## Background: Zeta‐chain associated protein of 70kDa (ZAP‐70) is the most promising surrogate marker for the immunoglobulin heavy chain variable region (IgV~H~) mutation status in B‐cell chronic lymphocytic leukemia (B‐CLL). Crespo et al. proposed the detection of ZAP‐70 by flow cytom