✦ LIBER ✦

Significant improvement of stiff-person syndrome after paraspinal injection of botulinum toxin A

✍ Scribed by Dave Davis; Dr. Bahman Jabbari

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 356 KB
Volume: 8
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.870080323

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Following several months of low back pain, a 36‐year‐old developed progressive stiffness of the abdominal, low back, and thigh muscles. On examination, these muscles demonstrated marked hypertonia consistent with the clinical diagnosis of stiff‐person syndrome. The patient demonstrated increased lumbar lordosis and had focal hyperhidrosis at different sites. Electromyography showed continuous activity of the paraspinal and thigh muscles, and serum and cerebrospinal fluid antibodies to glutamic acid decarboxylase (GAD) were markedly elevated. Diazepam and Lioresal offered partial pain relief. Paraspinal muscle administration of botulinum toxin A reduced the tone of paraspinal and thigh muscles significantly and resulted in marked improvement of ambulation and cessation of pain.

📜 SIMILAR VOLUMES

Botulinum toxin a improves muscle spasms

Botulinum toxin a improves muscle spasms and rigidity in stiff-person syndrome

✍ Dr. Rocco Liguori; Carla Cordivari; Elio Lugaresi; Pasquale Montagna 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 362 KB

We studied the effect of botulinum toxin A (BTA) on painful muscular spasms and rigidity in two bedridden patients with clinical, electrophysiologic, and immunologic evidence of stiff-person syndrome. We injected BTA or saline solution into several limb muscles with both the rater and patient blinde

Postneuroleptic laryngeal dyskinesias: A

Postneuroleptic laryngeal dyskinesias: A cause of upper airway obstructive syndrome improved by local injections of botulinum toxin

✍ Dr. A. Fève; B. Angelard; G. Fé;nelon; M. Logak; A. Guillard; J. Lacau Saint-Gui 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 259 KB

## Abstract We report a case of laryngeal dyskinesia resulting in severe rest and exercise dyspnea. A 51‐year‐old man treated for 2 years with flupentixol, an incisive neuroleptic, developed severe dyspnea due to intermittent, rhythmic, and dystonic movements of the vocal cords and upper airway. Lo

Botulinum toxin A injections improve apr

Botulinum toxin A injections improve apraxia of eyelid opening without overt blepharospasm associated with neurodegenerative diseases

✍ Masato Kanazawa; Takayoshi Shimohata; Masahisa Sato; Osamu Onodera; Keiko Tanaka 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 44 KB

Botulinum Toxin A Injections Improve Apraxia of Eyelid Opening without Overt Blepharospasm Associated with Neurodegenerative Diseases Apraxia of eyelid opening (AEO) designates an intermittent inability to open the eyes voluntarily. 1 AEO is observed in patients with neurodegenerative diseases, incl

Botulinum toxin A injections improve apr

Botulinum toxin A injections improve apraxia of eyelid opening without overt blepharospasm associated with neurodegenerative diseases

✍ Eva Lopez Valdes; Ignacio Javier Posada Rodriguez; Rafael Bilbao-Calabuig 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 34 KB

We have read with interest the letter of Kanazawa 1 about improvement of apraxia of eyelid opening (AEO) with botulinum toxin A. The term AEO defined as an intermittent inability to open the eyes voluntarily is not a specific entity; it is only a clinical sign whose physiopathological origin is var

Reply: Botulinum toxin A injections impr

Reply: Botulinum toxin A injections improve apraxia of eyelid opening without overt blepharospasm associated with neurodegenerative diseases

✍ Masato Kanazawa; Takayoshi Shimohata; Masatoyo Nishizawa 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 34 KB

Alteration of central motor excitability

Alteration of central motor excitability in a patient with hemimasticatory spasm after treatment with botulinum toxin injections

✍ Pablo Mir; Francesca Gilio; Mark Edwards; Maurizio Inghilleri; Kailash P. Bhatia 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB

## Abstract Hemimasticatory spasm (HMS) is a condition characterized by paroxysmal involuntary contraction of masticatory muscles. We performed an electrophysiological investigation of a single patient with HMS to identify any pathophysiological changes associated with the condition. We identified