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Significance of the Hardy–Weinberg equilibrium in genetic association studies

✍ Scribed by Mostafa Saadat

Book ID
116850403
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
104 KB
Volume
190
Category
Article
ISSN
0165-1781

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## Abstract Assessing Hardy‐Weinberg equilibrium (HWE) is often employed as an important initial step for genotype data quality checking in genetics studies. Tests for HWE often assume that the genotypes are randomly sampled from the general population. However, in many human genetics studies, subj