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Hardy–Weinberg equilibrium in genetic association studies: an empirical evaluation of reporting, deviations, and power

✍ Scribed by Salanti, Georgia; Amountza, Georgia; Ntzani, Evangelia E; Ioannidis, John P A

Book ID
110026314
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
173 KB
Volume
13
Category
Article
ISSN
1018-4813

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## Abstract The standard procedure to assess genetic equilibrium is a χ^2^ test of goodness‐of‐fit. As is the case with any statistical procedure of that type, the null hypothesis is that the distribution underlying the data is in agreement with the model. Thus, a significant result indicates incom