## Abstract Because of widely differing reports on the significance of IgM antiโHBc in chronic hepatitis B virus (HBV) infection, paired sera and liver biopsies from 49 patients with chronic HBV infection were analysed for serum IgM antiโHBc, HBsAg titre, HBeAgiantiโHBe, HBV DNA, serum aspartate tr
Significance of serial anti-HBc IgM detection in children with chronic hepatitis B
- Book ID
- 118566858
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 119 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0168-8278
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๐ SIMILAR VOLUMES
## Abstract Serum antiโHBc IgM titres were monitored monthly by a semiquantitative method in 14 children with HBeAg positive chronic hepatitis B followed up for 18โ65 months. All patients, but one, were treated with alfaโinterferon (IFN) at different times. On the whole, 12 flareโup episodes were o
IgM anti-HBc was measured by radioimmunoassay in se~rially collected serum samples during 20 acute exacerbations which developed in 14 patients with anti-HBe paeitive chronic type B hepatitis. IgM anti-HBc became @the in 12 of the 14 (86%) patients and in 18 of the 20 (90%) exacerbations, and elevat
The diagnostic significance of IgM antibody against hepatitis B core antigen (anti-HBc) in healthy hepatitis B surface antigen (HBsAg) carriers and in subjects affected by chronic hepatitis B was evaluated. IgM anti-HBc was sought and found in all nine patients examined who were affected by acute HB