Significance of chromosome 14 anomaly at band 14Q11 in Japanese patients with adult T-cell leukemia
β Scribed by Naoki Sadamori; Kenji Nishino; Miyuki Kusano; Yu Tomonaga; Masuko Tagawa; Ei-ichi Yao; Ippei Sasagawa; Hideo Nakamura; Michito Ichimaru
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 684 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Ip;&-3qChromosome I I, band q23, is the frequent site of recurring cytogenetic rearrangements in human leukemia. We have cloned and sequenced the breakpoint junctions from a patient who had null-cell acute lymphoblastic leukemia (ALL) with a t( I 1;14)(q23;ql I). The chromosome 14 breakpoints occurr
The MOLT-16 cell line was established from the leukemic cells of a patient with T-cell acute lymphoblastic leukemia and contains a t(8;14)(q24;q11) resulting in juxtaposition of sequences downstream of the MYC gene on chromosome 8 and the J region of the T-cell receptor alpha chain gene (TCRA) on ch
We performed cytogenetic analyses of peripheral blood lymphocytes from 82 Midwestern B-cell chronic lymphocytic leukemia (B-CLL) patients. The cells were cultured with mitogens for 3 4 days. At least I 5 metaphase cells were analyzed in 79 (96%) cases. Fifty (63%) of the 79 patients had clonal chrom
Nearly 30 percent of patients with T-cell acute lymphoblastic leukemia (T-ALL) exhibit a tumor-specific rearrangement of the TALI gene (also called TCLS or SCL). These rearrangements are generated by either local D N A deletion or a (I ; 14)(p34;q I I ) chromosome translocation, and they typically r