Signals regulating hepatitis B surface antigen transcription
β Scribed by Cattaneo, Roberto; Will, Hans; Hernandez, Nouria; Schaller, Heinz
- Book ID
- 109732132
- Publisher
- Nature Publishing Group
- Year
- 1983
- Tongue
- English
- Weight
- 441 KB
- Volume
- 305
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/305336a0
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## Abstract The presence of hepatitis B virus (HBV) genome, transcripts, and antigens (HBsAg, HBcAg, HBeAg) was examined in peripheral blood lymphocytes (PBL) from 12 patients with HBsAgβpositive (B) chronic active hepatitis (CAH) and 8 normal donors by Southern and Northern blot techniques and enz
Hepatitis B viral (HBV) mutants can emerge in patients as a result of selection pressure from treatment options. Some mutations that occur in the immunodominant ''a'' determinant of hepatitis B surface antigen (HBsAg) can present as false negative results in HBsAg immunoassays. The mutation position