Hepatitis B viral (HBV) mutants can emerge in patients as a result of selection pressure from treatment options. Some mutations that occur in the immunodominant ''a'' determinant of hepatitis B surface antigen (HBsAg) can present as false negative results in HBsAg immunoassays. The mutation position
Hepatitis B caused by a hepatitis B surface antigen escape mutant
โ Scribed by Eiji Kajiwara; Yasuhito Tanaka; Tomoko Ohashi; Kotarou Uchimura; Seizo Sadoshima; Mitsuru Kinjo; Masashi Mizokami
- Book ID
- 106180271
- Publisher
- Springer Japan
- Year
- 2008
- Tongue
- English
- Weight
- 209 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0944-1174
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๐ SIMILAR VOLUMES
HBsAg is the most important serological marker for acute or chronic hepatitis B. Nevertheless, there are reports of HBsAg-negative virus carriers, either with anti-HBc as the only marker for hepatitis B virus (HBV) infection or even positive for anti-HBs and anti-HBc. We report isolates from a patie
The increasing use of hepatitis B vaccination has had an overwhelming positive impact on the prevention of hepatitis B viral infection. Mutations in the hepatitis B surface antigen (HBsAg) gene occur as a result of vaccine escape mutants, anti-hepatitis B surface antigen immunotherapy, or in chronic