✦ LIBER ✦

Signalling: Stress and disease connect at mTORC1

✍ Scribed by Kritikou, Ekat

Book ID: 109948091
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 282 KB
Volume: 8
Category: Article
ISSN: 1474-1776
DOI: 10.1038/nrc2381

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## Abstract Numerous studies have shown that mammalian target of rapamycin (mTOR) inhibitor activates Akt signaling pathway via a negative feedback loop while inhibiting mTORC1 signaling. In this report, we focused on studying the role of mTORC1 and mTORC2 in rapamycin‐mediated Akt and ERK phosphor