𝔖 Bobbio Scriptorium
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Increased mTORC1 Signaling UPRegulates Stress

✍ Scribed by Jan H. Reiling; David M. Sabatini


Book ID
116754533
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
314 KB
Volume
29
Category
Article
ISSN
1097-2765

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## Abstract Numerous studies have shown that mammalian target of rapamycin (mTOR) inhibitor activates Akt signaling pathway via a negative feedback loop while inhibiting mTORC1 signaling. In this report, we focused on studying the role of mTORC1 and mTORC2 in rapamycin‐mediated Akt and ERK phosphor