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Signaling pathway analysis of MPP+-treated human neuroblastoma SH-SY5Y cells

โœ Scribed by Choi, Dong-Kug; Kim, In Su; Do, Jin Hwan


Book ID
125379828
Publisher
The Korean Society for Biotechnology and Bioengineering
Year
2014
Tongue
English
Weight
404 KB
Volume
19
Category
Article
ISSN
1226-8372

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A genetic defect in complex I of the mitochondrial electron transport chain (ETC) is implicated in the etiology of Parkinson's disease (PD), and has been studied in cybrid mitochondrial transgene cells based on the SH-SY5Y neuroblastoma. We sought to characterize further the mechanisms and time cour