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Genome-wide temporal responses of human neuroblastoma SH-SY5Y cells to MPP+neurotoxicity

✍ Scribed by Kim, In Su; Choi, Dong-Kug; Do, Jin Hwan


Book ID
121622384
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
408 KB
Volume
7
Category
Article
ISSN
1976-0280

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A genetic defect in complex I of the mitochondrial electron transport chain (ETC) is implicated in the etiology of Parkinson's disease (PD), and has been studied in cybrid mitochondrial transgene cells based on the SH-SY5Y neuroblastoma. We sought to characterize further the mechanisms and time cour