Cytokine receptor signaling mechanisms
β
Larry M. Karnitz; Robert T. Abraham
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Article
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1995
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Elsevier Science
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English
β 683 KB
Recent studies have dramatically advanced our understanding of the post-receptor signaling machinery engaged by members of the cytokine receptor superfamily. Proximal components of this signaling machinery are members of a novel class of protein tyrosine kinases termed JAKs. A working model proposes