Mutational activation of ErbB family rec
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David J. Riese II; Richard M. Gallo; Jeffrey Settleman
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Article
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2007
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John Wiley and Sons
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English
β 157 KB
π 1 views
## Abstract Signaling by the Epidermal Growth Factor Receptor (EGFR) and related ErbB family receptor tyrosine kinases can be deregulated in human malignancies as the result of mutations in the genes that encode these receptors. The recent identification of EGFR mutations that correlate with sensit