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Emerging recognition and activation mechanisms of receptor tyrosine kinases

✍ Scribed by He, Xiaolin


Book ID
122592714
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
136 KB
Volume
1834
Category
Article
ISSN
1570-9639

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## Abstract Signaling by the Epidermal Growth Factor Receptor (EGFR) and related ErbB family receptor tyrosine kinases can be deregulated in human malignancies as the result of mutations in the genes that encode these receptors. The recent identification of EGFR mutations that correlate with sensit