Signaling in response to hypoxia and normoxia in the intervertebral disc
β Scribed by Adele L. Boskey
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 46 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Although O~2~ concentrations are considerably lowered in vivo, depending on the tissue and cell population in question (some cells need almost anoxic environment for their maintenance) the cell and tissue cultures are usually performed at atmospheric O~2~ concentration (20β21%). As an i
## Abstract This study evaluated how dynamic compression induced changes in gene expression, tissue composition, and structural properties of the intervertebral disc using a rat tail model. We hypothesized that daily exposure to dynamic compression for short durations would result in anabolic remod
## Abstract Kinetics of mRNA expression following a single loading event was measured using an in vivo rat tail model. Animals were instrumented and loaded in compression for 1.5 h at 1 MPa and 1 Hz. Realβtime RTβPCR was used to measure mRNA levels 0, 8, 24 and 72 h after mechanical stimulation for
## Abstract Degeneration of the lumbar intervertebral disc (IVD) is a cause of low back pain. In osteoarthritis patients, an increase in Ξ²βcatenin accumulation has been reported. However, the molecular mechanisms involved in IVD remain unclear. In the present study, we examined the relationship of