Signaling by Distinct Classes of Phospho
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B. Vanhaesebroeck; M.D. Waterfield
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Article
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1999
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Elsevier Science
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English
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Many signaling pathways converge on and regulate phosphoinositide 3-kinase (PI3K) enzymes whose inositol lipid products are key mediators of intracellular signaling. Different PI3K isoforms generate specific lipids that bind to FYVE and pleckstrin homology (PH) domains in a variety of proteins, affe