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Signal transduction pathway activating interferon-alpha-stimulated gene expression

✍ Scribed by Susan A. Veals; Daniel S. Kessler; Serene Josiah; DebraG. B. Leonard; David E. Levy


Book ID
114712636
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
897 KB
Volume
79
Category
Article
ISSN
0007-1048

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## Abstract Interferon‐α (IFNΞ±) is a recombinant protein widely used in the therapy of several neoplasms such as myeloma, renal cell carcinoma, epidermoid cervical and head and neck tumors, and melanoma. IFNΞ±, the first cytokine to be produced by recombinant DNA technology, has emerged as an import