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Signal transduction during amyloid-β-peptide neurotoxicity: role in Alzheimer disease

✍ Scribed by Rodrigo A. Fuentealba; Ginny Farias; Jessica Scheu; Miguel Bronfman; María Paz Marzolo; Nibaldo C. Inestrosa

Book ID
116327552
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
536 KB
Volume
47
Category
Article
ISSN
0165-0173

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✍ Andrew B. Clippingdale; John D. Wade; Colin J. Barrow 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 334 KB

## Abstract Amyloid formation plays a central role in the cause and progression of Alzheimer's disease. The major component of this amyloid is the amyloid‐β (Aβ) peptide, which is currently the subject of intense study. This review discusses some recent studies in the area of Aβ synthesis, purifica