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Signal Response of Coexisting Protein Conformers in Electrospray Mass Spectrometry

✍ Scribed by Kuprowski, Mark C.; Konermann, Lars

Book ID
127352187
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
218 KB
Volume
79
Category
Article
ISSN
0003-2700

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## Abstract The influence of tertiary structure on the electrospray ionization mass spectra of proteins is a well known and broadly exploited phenomenon. However, the underlying mechanism is not well understood. This paper discusses the bases and the implications of the two current hypotheses (solv