## Abstract Membrane proteins drive and mediate many essential cellular processes making them a vital section of the proteome. However, the amphipathic nature of these molecules ensures their detailed structural analysis remains challenging. A versatile procedure for effective electrospray‐ionizati
Electrospray ionization-mass spectrometry conformational analysis of isolated domains of an intrinsically disordered protein
✍ Scribed by Lorenzo Testa; Stefania Brocca; Maria Šamalikova; Carlo Santambrogio; Lilia Alberghina; Dr. Rita Grandori
- Book ID
- 112012294
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 228 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1860-6768
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## Abstract The influence of tertiary structure on the electrospray ionization mass spectra of proteins is a well known and broadly exploited phenomenon. However, the underlying mechanism is not well understood. This paper discusses the bases and the implications of the two current hypotheses (solv