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Signal integration by JNK and p38 MAPK pathways in cancer development

✍ Scribed by Wagner, Erwin F.; Nebreda, Ángel R.

Book ID
109948379
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
427 KB
Volume
9
Category
Article
ISSN
1474-1776

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Mixed-lineage kinases (MLKs) are serine/threonine protein kinases that regulate signalling by the c-Jun amino-terminal kinase (JNK) and p38 mitogen-activated-protein kinase (MAPK) pathways. MLKs are represented in the genomes of both Caenorhabditis elegans and Drosophila melanogaster. The Drosophila